Abstract : The vital origin of liveliness in a human body is Glucose. In an organ system, brain cells and red blood cells are almost whole-body dependent on carbohydrates as the energy source. The production of energy from carbohydrates is 4 kcal per gram. The molecular formula of glucose is C6H12O6 and glucose is sweet in taste. Glucose is the subcategory of carbohydrates and overall, the most abundant monosaccharide, an important fuel for body. When an individual is well fed, the amount of circulating glucose comes mostly from the food eaten and when an individual is there in a fasting condition the two major metabolic cycles- gluconeogenesis and glycogenolysis are accountable for maintaining the glucose concentration.