Abstract : Iron is the nucleus of the iron porphyrin heme ring, which, when combined with globin chains, creates hemoglobin, which binds oxygen reversibly and is responsible for oxygen distribution from the lungs to other tissues. Microcytic hypochromic anemia is caused by the formation of small erythrocytes with inadequate hemoglobin due to the absence of iron. Anemia caused by inadequate of iron, vitamin B12, or folic acid is addressed in this section.