Abstract : In this analysis the body is divided into a definite number of well-mixed, interconnected, and kinetically homogenous compartments (e.g., blood, heart, liver, spleen, lungs, brain, muscle, organs, and other tissues). Based on this approach, the pharmacokineticist creates a hypotheses and develops nonlinear regression analysis models to represent the drug's PK. While utilising a compartmental anylsis, the output of the study may be variable because the assumptions utilised to develop the PK model may differ slightly from one pharmacokineticist to the next.
