Abstract : There is a great deal of information available on the relationship between drug absorption and physicochemical properties, and there is widespread agreement that passive diffusion absorption is largely governed by factors such as molecular size and shape, degree of ionisation, and solubility. It follows, then, that changes in a given agent's physicochemical state are more likely to affect its absorption if absorption is primarily a passive process. Only when a drug is administered as a solid and has a rate of dissolution slower than its rate of absorption can changes in the physicochemical state of an agent affect its absorption independent of the transport mode employed. Although modifications in drug properties have been the most effective and exploitable means of influencing drug absorption, only a few of the these changes have an effect on an agent's absorption once it is in solution. Pharmaceutical chemists have altered absorption in a variety of ways by altering the chemical form or formulation of a drug.
Keywords : ABSORPTION, Physicochemical, ii. Amorphism.
Cite : Sharma, M. K., & Ajmal, G. (2022). Factors Influencing Drug Absorption (1st ed., pp. 25-35). Noble Science Press. https://doi.org/10.52458/9789391842451.nsp2022.eb.asu.ch-04
