Abstract : The chloride anion in ephedrine hydrochloride is a weak acceptor of protons. When mercuric acetate is added, the chloride ion in this compound is exchanged for the acetate ion. When titrated against an acid like perchloric acid, acetate ions have a greater propensity to receive proton, which results in an accurate end point being obtained. In order to determine the concentration of ephedrine hydrochloride in glacial acetic acid, a predetermined amount of the hydrochloride is titrated with perchloric acid, and the end point is determined with the assistance of methyl orange solution as indicator.
Cite : Kumar, K., & Sharma, M. K. (2022). To Perform Assay Of Ephedrine Hydrochloride (Non-Aqueous Acid Base Titration) And Standardization Of Titrant (1st ed., p. 59). Noble Science Press. https://doi.org/10.52458/9789391842512.nsp2022.eb.asu.ch-10
